While Fabregas has a good chance of playing on March 8 Wenger fears Walcott could also miss the FA Cup replay against Leyton Orient next week.
Walcott could be missing in the Arsenal against Brcelona in Champions League
LONDON // The Arsenal forward Theo Walcott is likely to miss the Champions League last-16 second leg against Barcelona because of his ankle injury, manager Arsene Wenger has said.
The England winger was carried off during the 1-0 win over Stoke City on Wednesday and is definitely out of the League Cup final against Birmingham City on Sunday along with captain Cesc Fabregas.
But while Fabregas has a good chance of being fit for the return at the Nou Camp on March 8 Wenger fears Walcott could also miss that game and the FA Cup replay against Leyton Orient next week.
"Walcott will be out for two to three weeks with an ankle problem," Wenger said.
"I would say it is very unlikely he will be fit for the second leg of the Barcelona game.
"I imagine the worst so maybe I will be surprised in a positive way but I just give you my gut feeling at the moment."
Robin van Persie, who has missed the last two games through injury, will captain Arsenal on Sunday in the absence of Fabregas.
"I am delighted he is back," Wenger said. "He is the vice-captain and will captain the side because the captain cannot play."