The Serb takes on a temperamental Frenchman before the women slug it out for the semi-final spots at the All England Club on Tuesday.
Wimbledon 2017: Djokovic clash and women's quarter-finals to watch on Day 8
Adrian Mannarino v Novak Djokovic (2) - Centre Court, 3pm start A match that was scheduled for Monday, it got postponed only because of how long the Rafael Nadal-Gilles Muller encounter turned out to be. Djokovic is a strong favourite to win on Tuesday considering the form he has shown in the tournament. The Serb is also in contention to take back the men's No 1 ranking spot from Andy Murray if he wins Wimbledon, and he will do everything in his power to clinch the grass-court title for a fourth time. He seems rejuvenated under the watch of Andre Agassi and will be up to the challenge against a temperamental Mannarino who has run into trouble with the authorities at All England on several occasions. The fact that the Frenchman is moody and unafraid to take on the chair umpire might also make for good television.
Head-to-head Mannarino trails 1-0
Venus Williams (10) v Jelena Ostapenko (13) - Centre Court, second match This is a clash between two power hitters. Williams, 37, is a five-time Wimbledon champion, while Ostapenko - 17 years her junior - is a recent winner of the French Open title. The American changed tennis in the late 1990s when she introduced power to the women's game. The Latvian seems to be taking that element of power to another level, by combining it with some unconventional placement to finish points - and matches - more swiftly than ever before. However, the Latvian is yet untested against either of the Williams sisters, and how she deals with the experience of the older one will decide which way the match will go. Don't count on many rallies in this match.
Head-to-head First meeting
Johanna Konta (6) v Simona Halep (2) - Centre Court, third match Konta and Halep have brought their excellent form into the second week, with both players chasing their first grand slam title. Konta has the added pressure of ending a 40-year wait to become the first British woman to win a major. As for the Romanian, she can become world No 1 by reaching the semi-finals. In short, a lot rides on Tuesday's encounter. Both are aggressive players who won't shy away from the net in order to seize the initiative, so expect some exciting tennis. Halep has more experience and will probably be carrying the heartburn of having lost in major finals before, so she will be a slight favourite. But Konta will have plenty of support from the spectators.
Head-to-head Konta leads 2-0
Garbine Muguruza (14) v Svetlana Kuznetsova (7) - Court 1, 4pm start Kuznetsova reached her first Wimbledon quarter-final in 10 years to give herself a half-decent shot at a third grand slam title. But despite being seeded seven places higher than Muguruza, it is the latter who has a better chance of winning Tuesday's match. The Spanish-Venezuelan seems to have put a woeful year behind her and regained some of the touch that helped her to the French Open title in 2016. She claims to not be comfortable on grass, even wondering how she made it to the Wimbledon final in 2015, but she is an aggressive player who is beginning to back herself in crunch situations. It is how she managed to come from behind to beat world No 1 Angelique Kerber in the previous round. Her Russian opponent will not be a pushover, though, as she combines experience with tactical nous to make up for the fact that she is the wrong side of 30.
Head-to-head Muguruza leads 3-1
Magdalena Rybarikova v CoCo Vandeweghe (24) - Court 1, second match Slovakian Rybarikova has two advantages going into her first Wimbledon quarter-final on Tuesday - the confidence of having beaten top title contender Karolina Pliskova and the fact that she has defeated Vandeweghe both times the two players have met in a competitive match. But the American has been one of the most improved players of 2017 and has raised her game since hiring Pat Cash as coach. Vandeweghe is an aggressive player whose biggest problem, however, has been to rack up a lot of unforced errors. If she can keep that statistic in check, there is a good chance she will win on Tuesday.
Head-to-head Rybarikova leads 2-0