The Yankees record 4-3 victory over city rivals the Mets as title challengers slip up against the Washington Nationals.
MLB round-up: Yankees avenge Mets defeat
All four Yankees runs came in the seventh inning, Raul Ibanez levelling the match with a three-run homer before Eric Chavez also went yard.
And there was a further boost as nearest pursuers the Baltimore Orioles were beaten 3-1 by the Washington Nationals. Edwin Jackson pitched into the seventh inning and gave up just one hit and Adam LaRoche homered for the Nats, who lead the National League East ahead of the Mets.
The Atlanta Braves missed the chance to go second in the division when they were beaten 8-4 by the Boston Red Sox, whose in-form rookie Will Middlebrooks hit a solo homer and an RBI double.
The Chicago White Sox closed to within half a game of AL Central leaders the Cleveland Indians thanks to an 8-6 victory over the Milwaukee Brewers.
Dayan Viciedo piled up four runs including a two-run long ball as the Sox produced a performance in stark contrast to Friday's 10-inning 1-0 defeat.
The Indians went down 8-1 to the Houston Astros, Dallas Kuechel pitching a complete-game win in front of his parents in only his second Major League start.
The NL Central's leading pair, the Cincinnati Reds and the Pittsburgh Pirates, both enjoyed comfortable wins after strong showings by their pitchers.
Cincy's Johnny Cueto struck out nine in seven innings of three-hit ball and also drove in two runs in a 6-0 win over the Minnesota Twins.
Brad Lincoln allowed only two hits in six innings in Pittsburgh's 4-1 triumph over the Detroit Tigers, which was powered by Andrew McCutcheon's three-run homer.
The third-placed St Louis Cardinals beat the Kansas City Royals 8-2 to remain three games behind the Reds.
The Los Angeles Dodgers and the San Francisco Giants kept up their momentum in the NL West, the Dodgers beating city rivals the Angels 3-1 while San Francisco edged the Oakland Athletics 9-8. Brandon Belt homered and drove in three runs in a game which lasted over four hours and saw 12 pitchers throw 385 pitches.
AL West leaders the Texas Rangers failed to take advantage of the Angels' defeat as they went down 11-7 to the Colorado Rockies, with four runs coming from back-to-back singles by Tyler Colvin and Chris Nelson in the third.
Elsewhere, the Philadelphia Phillies beat the Tampa Bay Rays 7-6 on a walk-off homer by Jim Thome. The two sides' game on Friday night was rained off, meaning they will play a double-header on Sunday.
The Toronto Blue Jays hammered the Miami Marlins 7-1, the Seattle Mariners won 5-1 against the San Diego Padres and the Arizona Diamondbacks overcame the Chicago Cubs 10-5.
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