The LA pitcher threw eight dominant innings following his spell on the disabled list as the Dodgers defeated the Pirates 11-0.
MLB round-up: Billingsley continues comeback as Dodgers rout Pittsburg
Chad Billingsley impressed as the LA Dodgers recorded their fifth win in six Major League Baseball games in emphatic style.
Billingsley pitched eight dominant innings as the National League West leaders matched their highest-scoring game of the season, inflicting an 11-0 defeat on the Pittsburgh Pirates - their fifth defeat in six games.
The player had been on the disabled list due to elbow inflammation through the All-Star break, after losing all five of his previous outings before injury, but insists nothing has changed since returning to fitness.
"I've been throwing just fastballs and commanding the fastball pretty well lately, and just mixing in off-speed," he said.
"As far as my thought process, it hasn't changed."
Luis Cruz tied career highs for hits and RBIs with three each. Hanley Ramirez added three hits, two RBIs and two runs as Los Angeles beat the Pirates for the eighth straight time dating to last season.
Billingsley (9-9) won his fifth consecutive start, allowing five hits and one walk. He improved to 7-1 in his career against the Pirates.
Jon Jay and Matt Holliday each homered to put the St Louis Cardinals out in front of the Arizona Diamondbacks with an 8-2 series-opening win, while Tim Hudson was frugal in the Atlanta Braves' 6-0 win over the San Diego Padres.
Jimmy Rollins homered on the second pitch of the Philadelphia Phillies game against the Miami Marlins, providing the only offence in a Kyle Kendrick-Josh Johnson duel.
Jay Bruce hit a walk-off homer in the ninth inning of a 3-0 success over the New York Mets which gives the Cincinnati Reds a fourth successive victory.
The Chicago Cubs were no match for the Houston Astros, who won 10-1 at Wrigley Field, while the Detroit Tigers beat the Minnesota Twins - who did all their scoring in the third - 8-4.
A 4-0 eighth inning set up the San Francisco Giants' 6-1 win over the Washington Nationals - but a 3-0 final inning could not rescue the Milwaukee Brewers from an 8-6 loss to the Colorado Rockies.
In the American League, Jose Quintana recorded his first victory since July 5 as the Chicago White Sox beat the Toronto Blue Jays 3-2.
Mark Reynolds went deep twice, Omar Quintanilla added a solo homer and Wei-Yin Chen surrendered just one run over six-plus frames as the Baltimore Orioles downed the Boston Red Sox 7-1.
Nick Swisher snapped a scoreless tie with a seventh-inning homer as the New York Yankees sunk the Texas Rangers 3-0, while all the scoring in the Kansas City Royals' 5-0 win over the Oakland Athletics came in the fifth inning.
Elsewhere, the Seattle Mariners beat the Tampa Bay Rays 3-2 and the LA Angels defeated the Cleveland Indians 9-6.