AC Milan will take on Austria Vienna in Group D while Lazio are drawn against Nice in Group K.
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Arsenal face punishing away trips in their Europa League campaign after Friday's group stage draw pitted them against Bate Borisov and Red Star Belgrade, while Everton face a tough group including last season's semi-finalists Olympique Lyonnais.
Arsene Wenger's side, who failed to reach the Uefa Champions League for the first time since 1997, face a 4,500km round trip to face Belarusian champions Bate and can expect an intimidating atmosphere in their trip to Serbia to face Red Star. They will also meet Bundesliga side Cologne in Group H.
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Everton, the other Premier League side in the Europa League and who return to the competition after a three-year absence, take on Serie A side Atalanta in Group E, who are back in European football for the first time in 26 years.
Ronald Koeman's men will also face Cypriot side Apollon Limassol and Lyon, who were knocked out of the final four last season by eventual runners up Ajax.
AC Milan are among the favourites to win the tournament after spending more than €200 million (Dh866m) on new signings this season including Lucas Biglia, Andre Silva and Leonardo Bonucci. They will face Austria Vienna, HNK Rijeka and AEK Athens in Group D.