Ritz-Carlton has signed an agreement to take over the management from InterContinental Hotels Group of Al Bustan Palace, a luxury hotel in Muscat.
The management company is begin operating the property on Friday, Ritz-Carlton said. All the current employees will be kept on, the company said.
The property has recently undergone a multimillion-dollar refurbishment.
"The Omani capital has long been a key aspiration for The Ritz-Carlton and we have waited a long time to find the perfect opportunity," said Herve Humler, the president and chief operating officer of Ritz-Carlton.
The hotel has 250 rooms and suites, 200 acres of landscaped gardens and the longest beach in the country.
Ritz-Carlton this year opened its second hotel in Dubai at the Dubai International Financial Centre following delays after Union Properties sold the building while it was under development.
Ritz Carlton is also expanding its presence at Jumeirah Beach Residence.
It has a property under development in Abu Dhabi opposite the Fairmont Bab Al Bahr.
The resort, which will be the first under the brand in the capital, is scheduled to open at the end of this year, according to the property's developer, Abu Dhabi National Hotels.